Chang Jae Kim

From Tgi.kr

학력

  • 2004. 08 - 2008. 03 : 가톨릭 대학교 종양생물학과 졸업, 이학박사
  • 2002. 03 - 2004. 03 : 가톨릭 대학교 병리학과 졸업, 의학박사
  • 1995. 03 - 2002. 03 : 울산대학교 생명의과학과 졸업

 

이력

  • 2016. 08 - 현재      :  책임연구원, 게놈연구소(TGI), UNIST
  • 2008. 03 - 2016. 07 :  울산대학교병원 중점연구소

 

연구분야

  • 종양생물학
  • 분자생물학

논문

56. Kim JH, Jung SW, Byun SS, Shin JW, Park BR, Kim MH, Kim CJ, Park NH. Efficacy and safety of tenofovir in nucleos(t)ide-naïve patients with genotype C chronic hepatitis B in real-life practice. Int J Clin Pharm. 2015 Dec;37(6):1228-34.

55. Kim CJ, Shin JW, Jung SW, Park BR, Park NH. Somatic mutation of ARHI gene in Hepatocellular Carcinomas. Pathol Oncol Res. 2015 Sep;21(4):1277-9.

54. Kim BG, Jung SW, Kim EH, Kim JH, Park JH, Sung SJ, Park BR, Kim MH, Kim CJ, Lee BU, Park JH, Jeong ID, Bang SJ, Shin JW, Park NH. Tenofovir-based rescue therapy for chronic hepatitis B patients who had failed treatment with lamivudine, adefovir, and entecavir. J Gastroenterol Hepatol. 2015 Oct;30(10):1514-21.

53. Park JH, Jung SW, Park NH, Park BR, Kim MH, Kim CJ, Lee BU, Jeong ID, Kim BG, Bang SJ, Shin JW. Efficacy of Tenofovir-Based Rescue Therapy in Lamivudine-Resistant Chronic Hepatitis B Patients With Failure of Lamivudine and Adefovir Combination. Clin Ther. 2015 Jul 1;37(7):1433-42.

52. Lee GR, Jang SH, Kim CJ, Kim AR, Yoon DJ, Park NH, Han IS. Capsaicin suppresses the migration of cholangiocarcinoma cells by down-regulating matrix metalloproteinase-9 expression via the AMPK-NF-κB signaling pathway. Clin Exp Metastasis. 2014 Dec;31(8):897-907.

51. Kim CJ, Shin JW, Jung SW, Park BR, Cha HJ, Park NH. Mutational analysis of FEN1 Gene in hepatocellular carcinomas. APMIS. 2013 Oct 26. doi: 10.1111/apm.12202.

50. Jung SW, Park NH, Shin JW, Park BR, Kim CJ, Lee JE, Shin ES, Kim JA, Chung YH. Prognostic impact of telomere maintenance gene polymorphisms on hepatocellular carcinoma patients with chronic hepatitis B. Hepatology. 2014 May;59(5):1912-20.

49. Bang SJ, Kim BG, Shin JW, Ju HU, Park BR, Kim MH, Kim CJ, Park JH, Jeong ID, Jung SW, Park NH. Clinical course of patients with insufficient viral suppression during entecavir therapy in genotype C chronic hepatitis B. Dig Liver Dis. 2013 Jul;45(7):600-5.

48. Kim CJ, Lee GR, Shin JW, Jung SW, Park BR, Park NH. Mutational analysis of SATB1 gene in hepatocellular carcinomas. APMIS. 2013 Oct;121(10):1012-4.

47. Shin JW, Jung SW, Park BR, Kim CJ, Eum JB, Kim BG, Jeong ID, Bang SJ, Lee SH, Kim SR, Park NH. Prediction of response to entecavir therapy in patients with HBeAg-positive chronic hepatitis B based on on-treatment HBsAg, HBeAg and HBV DNA levels. J Viral Hepat. 2012 Oct;19(10):724-31.

46. Jung SW, Park NH, Shin JW, Park BR, Kim CJ, Lee JE, Shin ES, Kim JA, Chung YH. Polymorphisms of DNA repair genes in Korean hepatocellular carcinoma patients with chronic hepatitis B: possible implications on survival. J Hepatol. 2012 Sep;57(3):621-7.

45. Kim CJ, Park NH, Chung YH. Roads towards a new tailored therapy for hepatocellular carcinoma: diagnostic, therapeutic and prognostic implications of microRNAs. Liver Int. 2012 May;32(5):695-7.

44. Lee SJ, Shin JW, Park BR, Kim CJ, Jung SW, Kim B, Jeong ID, Bang SJ, Park NH. The expression kinetics of CD137 in chronic hepatitis C patients treated with pegylated-interferon and ribavirin. Scand J Gastroenterol. 2012 May;47(5):601-6.

43. Shin JW, Jung SW, Park BR, Kim CJ, Eum JB, Kim BG, Du Jeong I, Bang SJ, Park NH. HBV DNA level at 24 weeks is the best predictor of virological response to adefovir add-on therapy in patients with lamivudine resistance. Antivir Ther. 2012;17(2):387-94.

42. Shin JW, Park NH, Jung SW, Park BR, Kim CJ, Jeong ID, Bang SJ, Kim do H. Clinical sefulness of sequential hepatitis B virus DNA measurement (the roadmap concept) during adefovir treatment in lamivudine-resistant patients. Antivir Ther. 2009;14(2):181-6.

41. Hong SW, Kim CJ, Park WS, Shin JS, Lee SD, Ko SG, Jung SI, Park IC, An SK, Lee WK, Lee WJ, Jin DH, Lee MS. p34SEI-1 inhibits apoptosis through the stabilization of the X-linked inhibitor of apoptosis protein: p34SEI-1 as a novel target for anti-breast cancer strategies. Cancer Res. 2009 Feb 1;69(3):741-6.

40. Cao Z, Song JH, Kim CJ, Cho YG, Kim SY, Nam SW, Lee JY, Park WS. Absence of E17K mutation in the pleckstrin homology domain of AKT1 in gastrointestinal and liver cancers in the Korean population. APMIS. 2008 Jun;116(6):530-3.

39. Cao Z, Song JH, Kim CJ, Cho YG, Kim SY, Nam SW, Lee JY, Park WS. Genetic and epigenetic analysis of the VHL gene in gastric cancers. Acta Oncol. 2008;47(8):1551-6.

38. Kim CJ, Song JH, Cho YG, Cao Z, Kim SY, Nam SW, Lee JY, Park WS. Activation-induced Cytidine Deaminase Expression in Gastric Cancer. Tumour Biol. 2007;28(6):333-9.

37. Cho YG, Choi BJ, Song JH, Kim CJ, Cao Z, Nam SW, Lee JY, Park WS. No association of MDM2 T309G polymorphism with susceptibility to Korean gastric cancer patients. Neoplasma. 2008;55(3):256-60.

36. Kim CJ, Song JH, Cho YG, Cao Z, Lee YS, Nam SW, Lee JY, Park WS. Downregulation of ATBF1 is a Major Inactivating Mechanism in Hepatocellular Carcinomas. Histopathology. 2008 Apr;52(5):552-9.

35. Song JH, Kim CJ, Cho YG, Chae JS, Cao Z, Nam SW, Lee JY, Park WS. Genetic alterations of the Cdx2 gene in gastric cancer. APMIS. 2008 Jan;116(1):74-80.

34. Cho YG, Lee HS, Song JH, Kim CJ, Park YK, Nam SW, Yoo NJ, Lee JY, Park WS. KLF6 IVS1 -27G/A polymorphism with susceptibility to gastric cancers in Korean. Neoplasma. 2008;55(1):47-50.

33. Song JH, Lee HS, Kim CJ, Cho YG, Park YG, Nam SW, Lee JY, Park WS. Aspartic acid repeat polymorphism of the asporin gene with susceptibility to osteoarthritis of the knee in a Korean population. Knee. 2008 Jun;15(3):191-5.

32. Cho YG, Choi BJ, Kim CJ, Song JH, Zhang C, Nam SW, Lee JY, Park WS. Genetic analysis of the DBC2 gene in gastric cancer. Acta Oncol. 2008;47(3):366-71.

31. Cho YG, Song JH, Kim CJ, Nam SW, Yoo NJ, Lee JY, Park WS. Genetic and epigenetic analysis of the KLF4 gene in gastric cancer. APMIS. 2007 Jul;115(7):802-8.

30. Song JH, Kim CJ, Cho YG, Park YK, Nam SW, Yoo NJ, Lee JY, Park WS. Association of cyclin D1 G870A polymorphism with susceptibility to gastric cancers in Korean male patients. Neoplasma. 2007;54(3):235-9.

29. Kim CJ, Lee JH, Song JW, Cho YG, Kim SY, Nam SW, Yoo NJ, Park WS, Lee JY. Chk1 frameshift mutation in sporadic and hereditary non-polyposis colorectal cancers with microsatellite instability. Eur J Surg Oncol. 2007 Jun;33(5):580-5.

28. Kim CJ, Choi BJ, Song JH, Park YK, Cho YG, Nam SW, Yoo NJ, Lee JY, Park WS. Overexpression of serine-threonine receptor kinase-associated protein in colorectal cancers. Pathol Int. 2007 Apr;57(4):178-82.

27. Song JH, Kim CJ, Cho YG, Kwak HJ, Nam SW, Yoo NJ, Lee JY, Park WS. Genetic and epigenetic analysis of the EPHB2 gene in gastric cancers. APMIS. 2007 Feb;115(2):164-8.

26. Kim CJ, Song JH, Cho YG, Kim YS, Kim SY, Nam SW, Yoo NJ, Lee JY, Park WS. Somatic mutations of the beta-TrCP gene in gastric cancer. APMIS. 2007 Feb;115(2):127-33.

25. Kim CJ, Song JH, Cho YG, Chae HS, Nam SW, Yoo NJ, Lee JY, Park WS. Pin1 gene mutation is a rare event in gastric cancer. 1: APMIS. 2006 Jul-Aug;114(7-8):518-22.

24. Song J, Kim CJ, Cho YG, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS. Genetic and epigenetic alterations of the KLF6 gene in hepatocellular carcinoma. J Gastroenterol Hepatol. 2006 Aug;21(8):1286-9.

23. Cho YG, Choi BJ, Kim CJ, Song JW, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS. Genetic alterations of the KLF6 gene in colorectal cancers. APMIS. 2006 Jun;114(6):458-64.

22. Cho YG, Kim CJ, Song JH, Rhie DJ, Park YK, Kim SY, Nam SW, Yoo NJ, Lee JY, Park WS. Genetic and expression analysis of the KCNRG gene in hepatocellular carcinomas. Exp Mol Med. 2006 Jun 30;38(3):247-55.

21. Choi BJ, Cho YG, Song JW, Kim CJ, Kim SY, Nam SW, Yoo NJ, Lee JY, Park WS. Altered expression of the KLF4 in colorectal cancers. Pathol Res Pract. 2006;202(8):585-9.

20. Choi BJ, Kim CJ, Cho YG, Song JH, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS. Altered expression of CDX2 in colorectal cancers. APMIS. 2006 Jan;114(1):50-4.

19. Park WS, Cho YG, Kim CJ, Song JH, Lee YS, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY. Hypermethylation of the RUNX3 gene in hepatocellular carcinoma. Exp Mol Med. 2005 Aug 31;37(4):276-81.

18. Kim CJ, Cho YG, Park YG, Nam SW, Kim SY, Lee SH, Yoo NJ, Lee JY, Park WS. Pin1 overexpression in colorectal cancer and its correlation with aberrant beta-catenin expression. World  J  Gastroenterol. 2005 Aug 28;11(32):5006-9.

17. Cho YG, Kim CJ, Nam SW, Yoon SH, Lee SH, Yoo NJ, Lee JY, Park WS. Overexpression of S100A4 is closely associated with progression of colorectal cancer. World J Gastroenterol. 2005 Aug 21;11(31):4852-6.

16. Cho YG, Kim CJ, Park CH, Yang YM, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS. Genetic alterations of the KLF6 gene in gastric cancer. Oncogene. 2005 Jun 30;24(28):4588-90.

15. Kim CJ, Cho YG, Jeong SW, Kim YS, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS. Altered expression of KCNK9 in colorectal cancers. APMIS. 2004 Sep;112(9):588-94.

14. Kim CJ, Cho YG, Park CH, Jeong SW, Nam SW, Kim SY, Lee SH, Yoo NJ, Lee JY, Park WS. Inactivating mutations of the Siah-1 gene in gastric cancer. Oncogene.  2004 Nov 11;23(53):8591-6.

13. Kim CJ, Cho YG, Park CH, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS. Genetic alterations of the MYH gene in gastric cancer. Oncogene. 2004 Sep 2;23(40):6820-2.

12. Lee JH, Soung YH, Lee JW, Park WS, Kim SY, Cho YG, Kim CJ, Seo SH, Kim HS, Nam SW, Yoo NJ, Lee SH, Lee JY. Inactivating mutation of the pro-apoptotic gene BID in gastric cancer. J Pathol. 2004 Apr;202(4):439-45.

11. Lee JW, Soung YH, Kim SY, Nam SW, Kim CJ, Cho YG, Lee JH, Kim HS, Park WS, Kim SH, Lee JY, Yoo NJ, Lee SH. Inactivating mutations of proapoptotic Bad gene in human colon cancers. Carcinogenesis. 2004 Aug;25(8):1371-6.

10. Kim CJ, Cho YG, Park JY, Kim TY, Lee JH, Kim HS, Lee JW, Song YH, Nam SW, Lee SH, Yoo NJ, Lee JY, Park WS. Genetic analysis of the LKB1/STK11 gene in hepatocellular carcinomas. Eur J Cancer. 2004 Jan;40(1):136-41.

9. Lee JW, Yoo NJ, Soung YH, Kim HS, Park WS, Kim SY, Lee JH, Park JY, Cho YG, Kim CJ, Ko YH, Kim SH, Nam SW, Lee JY, Lee SH. BRAF mutations in non-Hodgkin's lymphoma. Br J Cancer. 2003 Nov 17;89(10):1958-60.

8. Lee SH, Lee JW, Soung YH, Kim HS, Park WS, Kim SY, Lee JH, Park JY, Cho YG, Kim CJ, Nam SW, Kim SH, Lee JY, Yoo NJ. BRAF and KRAS mutations in stomach cancer. Oncogene. 2003 Oct 9;22(44):6942-5.

7. Soung YH, Lee JW, Kim HS, Park WS, Kim SY, Lee JH, Park JY, Cho YG, Kim CJ, Park YG, Nam SW, Jeong SW, Kim SH, Lee JY, Yoo NJ, Lee SH. Inactivating mutations of CASPASE-7 gene in human cancers. Oncogene. 2003 Sep 11;22(39):8048-52.

6. Lee SH, Soung YH, Lee JW, Kim HS, Lee JH, Kim HS, Lee JH, Park JY, Cho YG, Kim CJ, Kim SY, Park WS, Kim SH, Lee JY, Yoo NJ. Mutational analysis of Noxa gene in human cancers. APMIS. 2003 Jun;111(6):599-604.

5. Kim HS, Lee JW, Soung YH, Park WS, Kim SY, Lee JH, Park JY, Cho YG, Kim CJ, Jeong SW, Nam SW, Kim SH, Lee JY, Yoo NJ, Lee SH. Inactivating mutations of caspase-8 gene in colorectal carcinomas. Gastroenterology. 2003 Sep;125(3):708-15.

4. Park WS, Cho YG, Park JY, Kim CJ, Lee JH, Kim HS, Lee JW, Song YH, Park CH, Park YK, Kim SY, Nam SW, Lee SH, Yoo NJ, Lee JY. A single nucleotide polymorphism in the E-cadherin gene promoter-160 is not associated with risk of Korean gastric cancer. J Korean Med Sci. 2003 Aug;18(4):501-4.

3. Cho YG, Nam SW, Kim TY, Kim YS, Kim CJ, Park JY, Lee JH, Kim HS, Lee JW, Park CH, Song YH, Lee SH, Yoo NJ, Lee JY, Park WS. Overexpression of S100A4 is closely related to the aggressiveness of gastric cancer. APMIS. 2003 May;111(5):539-45.

2. Kim HS, Lee SH, Lee JW, Soung YH, Lee JH, Park JY, Cho YG, Kim CJ, Kim SY, Lee YS, Park WS, Kim SH, Lee JY, Yoo NJ. Mutational analysis of Fas ligand gene in human non-Hodgkin lymphoma. APMIS. 2003 Apr;111(4):490-6.

1. Xiao W, Park CK, Park JY, Lee JH, Kim HS, Cho YG, Kim CJ, Ahn YM, Lee JH, Song YH, Lee SH, Yoo NJ, Lee JY, Park WS. Genetic alterations of the HCCS1 gene in Korean hepatocellular carcinoma. APMIS. 2003 Apr;111(4):465-73.